EVALUATION OF THE IMMUNOPROTECTIVE POTENTIAL OF RECOMBINANT PARAFLAGELLAR ROD PROTEINS OF TRYPANOSOMA EVANSI IN MICE

Evaluation of the Immunoprotective Potential of Recombinant Paraflagellar Rod Proteins of Trypanosoma evansi in Mice

Trypanosomosis, caused by Trypanosoma evansi, is an economically significant disease Knife Rack of livestock.Systematic antigenic variation by the parasite has undermined prospects for the development of a protective vaccine that targets the immunodominant surface antigens, encouraging exploration of alternatives.The paraflagellar rod (PFR), consti

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Susceptibility of pancreatic beta cells to fatty acids is regulated by LXR/PPARalpha-dependent stearoyl-coenzyme A desaturase.

Chronically elevated levels of fatty acids-FA can cause beta cell death in vitro.Beta cells vary in their individual susceptibility to FA-toxicity.Rat beta cells were previously shown to better resist FA-toxicity in conditions that increased triglyceride formation or mitochondrial and peroxisomal FA-oxidation, possibly reducing cytoplasmic levels o

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Searching Explanations of Nature in the Mirror World of Math

Despite the huge scientific progress of the last century, the dynamics of complex systems such as the atmosphere, human societies, and ecosystems remain difficult to understand and predict.Nonetheless, our ability to carve the future Lamps depends largely on our insight into the functioning of such complex systems.Complex systems are the focus of c

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Performance estimation of two in-house ELISA assays for COVID-19 surveillance through the combined detection of anti-SARS-CoV-2 IgA, IgM, and IgG immunoglobulin isotypes.

The main objective of this study was to estimate the performance, under local epidemiological conditions, of two in-house ELISA assays for the combined detection of anti-SARS-CoV-2 IgA, IgM, and IgG immunoglobulins.A total of 94 serum samples were used for the assessment, where 44 corresponded to sera collected before the pandemic (free of SARS-CoV

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